Any feedback?
Literature summary for 3.4.24.85 extracted from
- Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2 (2007), Int. J. Biochem. Cell Biol., 39, 1843-1851.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| A23187 | - |
Homo sapiens |  |
| homocysteine | - |
Homo sapiens | |
| thapsigargin | cells treated with thapsigargin exhibit proteolytic cleavage of SREBP-2 | Homo sapiens | |
| tunicamycin | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HeLa cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| SREBP NH2-522 fragment + H2O | - |
Homo sapiens | NH2-484 fragment + 38 aa fragment | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| site-2 protease | - |
Homo sapiens |
| SREBP-2 proteinase | - |
Homo sapiens |
| sterol regulatory element binding protein-2 proteinase | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2026.1 (March 2026)
Legal
Curated at
Member of
![DSMZ Digital Diversity]()
![Global Core Biodata Resource]()
![ELIXIR Core Data Resource]()
![German Network for Bioinformatics Infrastructure]()
