Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
68000 | - |
x * 68000, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q9ESP7 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
brevican + H2O | - |
Rattus norvegicus | ? | - |
? | |
neurocan + H2O | - |
Rattus norvegicus | ? | - |
? | |
phosphacan + H2O | - |
Rattus norvegicus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 68000, SDS-PAGE | Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | ADAMTS-4 digests proteoglycans, and reverses their inhibition of neurite outgrowth. Local administration of ADAMTS-4 significantly promotes motor function recovery after spinal cord injury. The ADAMTS-4-treated spinal cord exhibits enhanced axonal regeneration/sprouting after spinal cord injury | Rattus norvegicus |