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Literature summary for 3.4.24.79 extracted from

  • Harstad, S.; Conover, C.
    Tissue-specific changes in pregnancy associated plasma protein-A expression with age in mice (2014), Exp. Gerontol., 57, 13-17 .
    View publication on PubMedView publication on EuropePMC

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc metalloproteinase Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
insulin-like growth factor binding protein-4 + H2O Mus musculus
-
?
-
?
insulin-like growth factor binding protein-5 + H2O Mus musculus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus Q8R4K8
-
-

Source Tissue

Source Tissue Comment Organism Textmining
abdominal adipose tissue highest expression Mus musculus
-
bone
-
Mus musculus
-
brain
-
Mus musculus
-
gonad
-
Mus musculus
-
kidney
-
Mus musculus
-
additional information not expressed in liver Mus musculus
-
skeletal muscle
-
Mus musculus
-
subcutaneous adipose tissue
-
Mus musculus
-
thymus
-
Mus musculus
-
tibia
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
insulin-like growth factor binding protein-4 + H2O
-
Mus musculus ?
-
?
insulin-like growth factor binding protein-5 + H2O
-
Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
PAPP-A
-
Mus musculus
pregnancy associated plasma protein-A
-
Mus musculus

Expression

Organism Comment Expression
Mus musculus enzyme expression significantly decreases with age in bone and skeletal muscle down
Mus musculus enzyme expression significantly increases with age in kidney, brain and gonads up