Literature summary for 3.4.24.79 extracted from

Mazerbourg, S.; Overgaard, M.T.; Oxvig, C.; Christiansen, M.; Conover, C.A.; Laurendeau, I.; Vidaud, M.; Tosser-Klopp, G.; Zapf, J.; Monget, P.
Pregnancy-associated plasma protein-A (PAPP-A) in ovine, bovine, porcine, and equine ovarian follicles: involvement in IGF binding protein-4 proteolytic degradation and mRNA expression during follicular development (2001), Endocrinology, 142, 5243-5253.

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Activating Compound

Activating Compound	Comment	Organism	Structure
IGF	PAPP-A activity is dependent on presence of insulin-like growth factor	Sus scrofa
IGF	PAPP-A activity is dependent on presence of insulin-like growth factor	Bos taurus
IGF	PAPP-A activity is dependent on presence of insulin-like growth factor	Equus caballus
IGF	PAPP-A activity is dependent on presence of insulin-like growth factor	Ovis ammon

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-
Equus caballus	-	-	-
Ovis ammon	-	-	-
Sus scrofa	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
ovarian follicle	-	Sus scrofa	-
ovarian follicle	-	Bos taurus	-
ovarian follicle	-	Equus caballus	-
ovarian follicle	-	Ovis ammon	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
insulin-like growth factor binding protein-4 + H2O	-	Sus scrofa	?	-	?
insulin-like growth factor binding protein-4 + H2O	-	Bos taurus	?	-	?
insulin-like growth factor binding protein-4 + H2O	-	Equus caballus	?	-	?
insulin-like growth factor binding protein-4 + H2O	-	Ovis ammon	?	-	?

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Release 2023.1 (January 2023)