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Literature summary for 3.4.24.74 extracted from

  • Choi, V.M.; Herrou, J.; Hecht, A.L.; Teoh, W.P.; Turner, J.R.; Crosson, S.; Bubeck Wardenburg, J.
    Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice (2016), Nat. Med., 22, 563-567 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.74

Activating Compound

Activating Compound Comment Organism Structure
fragipain
-
 Bacteroides fragilis ATCC 43858

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Origami-2 cells Bacteroides fragilis ATCC 43858

Organism

Organism UniProt Comment Textmining
Bacteroides fragilis ATCC 43858 A0A164V5U8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
E-cadherin + H2O
-
 Bacteroides fragilis ATCC 43858 ?
-
 ?

Subunits

Subunits Comment Organism
? x * 45000, zymogen, SDS-PAGE Bacteroides fragilis ATCC 43858

Synonyms

Synonyms Comment Organism
B. fragilis enterotoxin
-
 Bacteroides fragilis ATCC 43858
Bacteroides fragilis toxin
-
 Bacteroides fragilis ATCC 43858
BFT
-
 Bacteroides fragilis ATCC 43858

General Information

General Information Comment Organism
physiological function the enzyme contributes to anaerobic sepsis. The colonic epithelial barrier is an important target of the enzyme Bacteroides fragilis ATCC 43858