Application | Comment | Organism |
---|---|---|
additional information | intestinal epithelial cells in vitro possess a specific membrane BFT receptor that is distinct from E-cadherin | Bacteroides fragilis |
Protein Variants | Comment | Organism |
---|---|---|
H352Y | Alexa-488-labeled BFT binding to HT29/C1 not blocked | Bacteroides fragilis |
additional information | BFT-C4, which has reduced BFT biological activity, shows a significant decrease in HT29/C1 cell binding | Bacteroides fragilis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
germ agglutinin | inhibits BFT biological activity on HT29/C1 cells but not binding of Alexa 488-labeled BFT to HT29/C1 cells | Bacteroides fragilis | |
GM6001 | significantly reduces Alexa 488-labeled BFT binding | Bacteroides fragilis | |
additional information | not inhibited by lectins, sugars or mixed bovine brain gangliosides | Bacteroides fragilis | |
subtilisin A | inhibits both BFT biological activity on HT29/C1 cells and nearly 90% of binding of Alexa 488-labeled BFT | Bacteroides fragilis | |
Thermolysin | inhibits both BFT biological activity on HT29/C1 cells and nearly 90% of binding of Alexa 488-labeled BFT | Bacteroides fragilis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacteroides fragilis | - |
- |
- |
Bacteroides fragilis I-1345 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
purified to homogeneity by urea-based purification method | Bacteroides fragilis |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
E-cadherin + H2O | neither human nor rat E-cadherin are the cellular receptor for BFT | Bacteroides fragilis | ? | - |
? | |
E-cadherin + H2O | neither human nor rat E-cadherin are the cellular receptor for BFT | Bacteroides fragilis I-1345 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Bacteroides fragilis toxin | - |
Bacteroides fragilis |
BFT | - |
Bacteroides fragilis |