Application | Comment | Organism |
---|---|---|
medicine | in MMP-12 deficient mice, deficiency has no significant effect on total body weight or on subcutaneous or gonadal adipose tissue mass. Adipocyte and blood vessel size and density in subcutaneous and gonadal adipose tissues of obese mice are also comparable in MMP-12 deficient and control mice. Macrophage infiltration in subcutaneous and gonadal adipose tissues is not affected by MMP-12 deficiency, but the amount of crown-like structures is significantly lower. MMP-12 deficiency does not affect elastin content in the extracellular matrix of subcutaneous or gonadal adipose tissue | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P34960 | - |
- |
Source Tissue | Comment | Organism | Textmining |
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General Information | Comment | Organism |
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physiological function | in MMP-12 deficient mice, deficiency has no significant effect on total body weight or on subcutaneous or gonadal adipose tissue mass. Adipocyte and blood vessel size and density in subcutaneous and gonadal adipose tissues of obese mice are also comparable in MMP-12 deficient and control mice. Macrophage infiltration in subcutaneous and gonadal adipose tissues is not affected by MMP-12 deficiency, but the amount of crown-like structures is significantly lower. MMP-12 deficiency does not affect elastin content in the extracellular matrix of subcutaneous or gonadal adipose tissue | Mus musculus |