Literature summary for 3.4.24.22 extracted from

Heo, S.H.; Choi, Y.J.; Ryoo, H.M.; Cho, J.Y.
Expression profiling of ETS and MMP factors in VEGF-activated endothelial cells: role of MMP-10 in VEGF-induced angiogenesis (2010), J. Cell. Physiol., 224, 734-742.

Search for more literature for 3.4.24.22

Cloned(Commentary)

Cloned (Comment)	Organism
MMP-10 DNA and amino acid sequence determination and expression analysis in HUVECs, transcriptional regulation of MMP-10 by Ets transcription factors, overview	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	MMP-10 knockdown by siRNA	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P09238	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
umbilical vein endothelial cell	HUVEC, quantitative RT-PCR of MMPs, overview	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
MMP-10	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	PD98059 and SP600125, ERK and JNK inhibitors, respectively, repress VEGF-induced MMP-10 expression to mRNA expression levels lower than the basal expression of MMP-10	down
Homo sapiens	VEGF165 induces MMP-10 expression about 2fold. LY294002 inhibits VEGF-induced MMP-10 expression, indicating the involvement of PI3K in VEGF-induced MMP-10 expression	up

General Information

General Information	Comment	Organism
malfunction	MMP-10 plays a critical role in VEGF-induced angiogenesis, overview	Homo sapiens
additional information	transcriptional regulation of MMP-10 by Ets transcription factors	Homo sapiens

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Release 2023.1 (January 2023)