Literature summary for 3.4.24.22 extracted from

Richardson, S.M.; Doyle, P.; Minogue, B.M.; Gnanalingham, K.; Hoyland, J.A.
Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc (2009), Arthritis Res. Ther., 11, R126.

Search for more literature for 3.4.24.22

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	-	Homo sapiens	-	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	MMP-10 is a potent activator of a number of MMP pro-enzymes, including pro-MMP-1, -7, -8, -9 and -13	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
chondrocyte	-	Homo sapiens	-
additional information	gene expression of interleukin-1, nerve growth factor, and tumour necrosis factor-alpha does not correlate with matrix metalloproteinase-10 in human nucleus pulposus, but expression of substance P does correlate with MMP-10 expression, overview	Homo sapiens	-
nucleus pulposus	postmortem or following surgery	Homo sapiens	-
spinal cord	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	MMP-10 is a potent activator of a number of MMP pro-enzymes, including pro-MMP-1, -7, -8, -9 and -13	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
Matrix metalloproteinase-10	-	Homo sapiens
MMP-10	-	Homo sapiens
More	MMP-10 or stromelysin-2 is a member of the stromelysin family of enzymes	Homo sapiens
stromelysin-2	-	Homo sapiens

General Information

General Information	Comment	Organism
metabolism	MMP-10 is a potent activator of a number of MMP pro-enzymes, including pro-MMP-1, -7, -8, -9 and -13	Homo sapiens
additional information	gene expression of interleukin-1, nerve growth factor, and tumour necrosis factor-alpha does not correlate with matrix metalloproteinase-10 in human nucleus pulposus, but expression of substance P does correlate with MMP-10 expression, overview	Homo sapiens

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Release 2023.1 (January 2023)