Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.11 extracted from

  • Oefner, C.; Pierau, S.; Schulz, H.; Dale, G.E.
    Structural studies of a bifunctional inhibitor of neprilysin and DPP-IV (2007), Acta Crystallogr. Sect. D, 63, 975-981.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
MCB3937 bifunctional inhibitor of NEP and DPP-IV Homo sapiens
MCB4241 bifunctional inhibitor of NEP and DPP-IV Homo sapiens
thiorphan
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P08473
-
-

Synonyms

Synonyms Comment Organism
CALLA
-
Homo sapiens
CD10
-
Homo sapiens
enkephalinase
-
Homo sapiens
NEP
-
Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000004
-
thiorphan
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00045
-
-
Homo sapiens MCB3937
0.0006
-
-
Homo sapiens MCB4241