Any feedback?
Literature summary for 3.4.23.5 extracted from
- New functional aspects of cathepsin D and cathepsin E (2000), Mol. Cells, 10, 601-611.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | enzyme secreted from prostate carcinoma cells is responsible for generation of angiostatin, pro-enzyme from breast cancer cells shows significantly lower angiostatin-generating activity than that from prostate carcinoma cells | Homo sapiens |
| medicine | mice deficient in enzyme show progressive atrophy of intestinal mucosa, a massive destruction of lymphoid organs, and a profound accumulation of ceroid lipofuscin | Mus musculus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | mice deficient in enzyme show progressive atrophy of intestinal mucosa, a massive destruction of lymphoid organs, and a profound accumulation of ceroid lipofuscin | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| carcinoma cell | prostate carcinoma, breast carcinoma | Homo sapiens | - |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
