Any feedback?
Literature summary for 3.4.23.45 extracted from
- Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2 (2010), Genes Brain Behav., 9, 160-172.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| mouse model overexpresing BACE2 | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | in a mouse model of in vivo BACE2 overexpression, BACE2 is not involved in the amyloidogenic pathway, cognitive dysfunction or cholinergic degeneration. Transgenic BACE2 animals show increased anxiety-like behaviour along with increased numbers of noradrenergic neurones in locus coeruleus | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
