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Literature summary for 3.4.22.B71 extracted from

  • Lu, H.; Liu, B.; You, S.; Chen, L.; Dongmei, Q.; Gu, M.; Lu, Y.; Chen, Y.; Zhang, F.; Yu, B.
    SENP2 regulates MEF2A de-SUMOylation in an activity dependent manner (2013), Mol. Biol. Rep., 40, 2485-2490.
    View publication on PubMed
Search for more literature for 3.4.22.B71

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Homo sapiens 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
SUMOylated myocyte-specific enhancer factor-2A + H2O Homo sapiens deSUMOylation by enzyme SENP2 deSUMOylated myocyte-specific enhancer factor-2A + SUMO
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neuroblastoma cell
-
 Homo sapiens
-
SH-SY5Y cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
SUMOylated myocyte-specific enhancer factor-2A + H2O deSUMOylation by enzyme SENP2 Homo sapiens deSUMOylated myocyte-specific enhancer factor-2A + SUMO
-
 ?

Synonyms

Synonyms Comment Organism
SENP2
-
 Homo sapiens

General Information

General Information Comment Organism
metabolism SENP2 protein is accumulated in response to activity-dependent stimuli which in turn mediated activity dependent-regulation of MEF2A deSUMOylation Homo sapiens
physiological function SENP2, but not SENP1, regulates MEF2A deSUMOylation in an activity dependent manner, enzyme SENP2 markedly enhances the transcription of MEF2A through directly deSUMOylation Homo sapiens