Literature summary for 3.4.22.B70 extracted from

Rodriguez-Castaneda, F.; Lemma, R.B.; Cuervo, I.; Bengtsen, M.; Moen, L.M.; Ledsaak, M.; Eskeland, R.; Gabrielsen, O.S.
The SUMO protease SENP1 and the chromatin remodeler CHD3 interact and jointly affect chromatin accessibility and gene expression (2018), J. Biol. Chem., 293, 15439-15454 .

Search for more literature for 3.4.22.B70

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9P0U3	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HAP-1 cell	-	Homo sapiens	-
HEK-293 cell	-	Homo sapiens	-
K-562 cell	-	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	SENP1 physically interacts with the chromatin remodeler chromodomain helicase DNA-binding protein CHD3. CHD3-and SENP1-KO cells reveal a large degree of overlap in differential chromatin openness between these two mutant cell lines. CHD3 and SENP1 may associate with CCCTC-binding factor (CTCF) and SUMOylated chromatin-associated factors. SENP1 and CHD3 proteins co-regulate the expression of several genes	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)