Literature summary for 3.4.22.B49 extracted from

Kueakhai, P.; Changklungmoa, N.; Chaichanasak, P.; Jaikua, W.; Itagaki, T.; Sobhon, P.
Vaccine potential of recombinant pro- and mature cathepsin L1 against fasciolosis gigantica in mice (2015), Acta Trop., 150, 71-78 .

Search for more literature for 3.4.22.B49

Application

Application	Comment	Organism
medicine	vaccination of mice by subcutaneous injection with recombinant proFgCatL1 and recombinant mature FgCatL1 combined with Freund's adjuvant. Two weeks after the second boost, mice are infected with 15 metacercariae by the oral route. The level of protection of rproFgCatL1 and rmatFgCatL1 vaccines is estimated to be 39.1-41.7% and 44.9-47.2% when compared with non vaccinated-infected and adjuvant-infected controls, respectively. Antibodies in the immune sera of vaccinated mice are shown by immunoblotting to react with the native FgCatL1 in the extract of newly excysted juveniles (NEJ), 4-week-old juveniles, and the excretory-secretory products of 4 week-old juveniles. rFgCatL1 has a potential as a vaccine candidate against Fasciola gigantica in mice, and might also be effective in ruminants	Fasciola gigantica

Cloned(Commentary)

Cloned (Comment)	Organism
gene cat-L1, recombinant expression of pro-enzyme and mature enzyme in Escherichia coli strain BL21(DE3)	Fasciola gigantica

Organism

Organism	UniProt	Comment	Textmining
Fasciola gigantica	Q9XYL8	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Synonyms

Synonyms	Comment	Organism
CatL1	-	Fasciola gigantica

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Release 2023.1 (January 2023)