Literature summary for 3.4.22.B49 extracted from

Miysato, P.; Ramos, C.; Abreu, P.; Dias, W.; Nascimento, C.; Ho, P.; Kawano, T.
Expression of schistosomal cathepsin L1 in Escherichia coli and evaluation of its protective capacity in an animal challenge (2009), J. Venom. Anim. Toxins incl. Trop. Dis., 15, 289-304.

No PubMed abstract available

Search for more literature for 3.4.22.B49

Application

Application	Comment	Organism
medicine	mice immunized with recombinant CL1 show a decrease of 21.8% in Schistosoma mansoni burden	Schistosoma mansoni

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21-SI cells	Schistosoma mansoni

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
36950	-	recombinant protein, calculated from amino acid sequence	Schistosoma mansoni
37000	-	recombinant protein, SDS-PAGE	Schistosoma mansoni

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
Hemoglobin + H2O	Schistosoma mansoni	purified recombinant CL1 is not able to hydrolyze hemoglobin	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Schistosoma mansoni	Q26534	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-Sepharose resin column chromatography, gel filtration	Schistosoma mansoni

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Hemoglobin + H2O	purified recombinant CL1 is not able to hydrolyze hemoglobin	Schistosoma mansoni	?	-	?

Synonyms

Synonyms	Comment	Organism
CL1	-	Schistosoma mansoni

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Release 2023.1 (January 2023)