BRENDA - Enzyme Database show
show all sequences of 3.4.22.8

Investigations on the enzyme specificity of clostripain: a new efficient biocatalyst for the synthesis of peptide isosteres

Gunther, R.; Stein, A.; Bordusa, F.; J. Org. Chem. 65, 1672-1679 (2000)

Data extracted from this reference:

Application
Application
Commentary
Organism
synthesis
efficient biocatalyst for the synthesis of peptide isosteres
Hathewaya histolytica
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Hathewaya histolytica
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
benzoyl-Arg ethyl ester + 3-amino-propionamide
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-3-amino-propionamide
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 3-amino-propionic acid methyl ester
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-3-amino-propionic acid methyl ester
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 4-amino-butyramide
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-4-amino-butyramide
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 4-amino-butyric acid methyl ester
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-4-amino-butyric acid methyl ester
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 5-amino-pentanoic acid
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-5-amino-pentanoic acid
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 5-amino-pentanoic acid amide
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-5-amino-pentanoic acid amide
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 5-amino-pentanoic acid methyl ester
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-5-amino-pentanoic acid methyl ester
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 6-amino-hexanoic acid
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-6-amino-hexanoic acid
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 6-amino-hexanoic acid amide
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-6-amino-hexanoic acid amide
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 6-amino-hexanoic acid methyl ester
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-6-amino-hexanoic acid methyl ester
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 9-amino-nonanoic acid
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-9-amino-nonanoic acid
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 9-amino-nonanoic acid amide
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-9-amino-nonanoic acid amide
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 9-amino-nonanoic acid methyl ester
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-9-amino-nonanoic acid methyl ester
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + 2-amino-4-methyl-pentan-1-ol
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-2-amino-4-methyl-pentan-1-ol
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + 3-amino-propane-1,2-diol
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-3-amino-propane-1,2-diol
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + 3-amino-propanol
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-3-amino-propanol
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + 5-amino-pentanol
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-5-amino-pentanol
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + cycloheptylamine
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-cycloheptylamide
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + pentylamine
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-pentylamide
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + propylamine
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-propylamide
-
652992
Hathewaya histolytica
?
Application (protein specific)
Application
Commentary
Organism
synthesis
efficient biocatalyst for the synthesis of peptide isosteres
Hathewaya histolytica
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
benzoyl-Arg ethyl ester + 3-amino-propionamide
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-3-amino-propionamide
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 3-amino-propionic acid methyl ester
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-3-amino-propionic acid methyl ester
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 4-amino-butyramide
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-4-amino-butyramide
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 4-amino-butyric acid methyl ester
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-4-amino-butyric acid methyl ester
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 5-amino-pentanoic acid
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-5-amino-pentanoic acid
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 5-amino-pentanoic acid amide
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-5-amino-pentanoic acid amide
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 5-amino-pentanoic acid methyl ester
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-5-amino-pentanoic acid methyl ester
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 6-amino-hexanoic acid
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-6-amino-hexanoic acid
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 6-amino-hexanoic acid amide
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-6-amino-hexanoic acid amide
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 6-amino-hexanoic acid methyl ester
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-6-amino-hexanoic acid methyl ester
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 9-amino-nonanoic acid
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-9-amino-nonanoic acid
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 9-amino-nonanoic acid amide
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-9-amino-nonanoic acid amide
-
652992
Hathewaya histolytica
?
benzoyl-Arg ethyl ester + 9-amino-nonanoic acid methyl ester
-
652992
Hathewaya histolytica
ethanol + benzoyl-Arg-9-amino-nonanoic acid methyl ester
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + 2-amino-4-methyl-pentan-1-ol
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-2-amino-4-methyl-pentan-1-ol
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + 3-amino-propane-1,2-diol
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-3-amino-propane-1,2-diol
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + 3-amino-propanol
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-3-amino-propanol
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + 5-amino-pentanol
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-5-amino-pentanol
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + cycloheptylamine
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-cycloheptylamide
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + pentylamine
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-pentylamide
-
652992
Hathewaya histolytica
?
benzoyl-Phe 4-guanidinephenyl ester + propylamine
-
652992
Hathewaya histolytica
4-guanidinephenol + benzoyl-Phe-propylamide
-
652992
Hathewaya histolytica
?
Other publictions for EC 3.4.22.8
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
718180
Bhattacharya
An efficient synthesis of benz ...
Hathewaya histolytica
Org. Biomol. Chem.
9
5407-5413
2011
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16
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1
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1
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16
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16
16
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1
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718284
Chakravorty
The cysteine protease alpha-cl ...
Clostridium perfringens, Clostridium perfringens JIR325
PLoS ONE
6
e22762
2011
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2
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2
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2
2
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718358
Tanaka
High-level production and puri ...
Hathewaya histolytica, Hathewaya histolytica ATCC 19401
Protein Expr. Purif.
76
83-89
2011
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-
1
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2
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8
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4
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1
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4
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1
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8
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4
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1
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2
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2
2
718452
Jankowska-Steifer
-
Vacuolating, lethal, collagena ...
Hathewaya histolytica, Hathewaya histolytica ATCC 17859, Hathewaya histolytica ATCC 17860, Hathewaya histolytica ATCC 19401, Hathewaya histolytica ATCC 25770, Hathewaya histolytica ATCC 6282, Hathewaya histolytica ATCC 8034
World J. Microbiol. Biotechnol.
27
1689-1694
2011
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1
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7
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1
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7
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1
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1
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7
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709851
Manabe
Purification and characterizat ...
Clostridium perfringens 13, Clostridium perfringens
Microbiology
156
561-569
2010
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1
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2
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1
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6
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1
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4
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6
1
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2
1
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1
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1
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1
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4
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6
1
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2
1
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2
2
686000
Guzik
A new insight into phagocytosi ...
Hathewaya histolytica
Cell Death Differ.
14
171-182
2007
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2
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1
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687876
Kim
Secretory expression of active ...
Clostridium sp.
J. Biotechnol.
131
346-352
2007
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1
1
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1
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668643
Jozwiak
Determination of the cytotoxic ...
Hathewaya histolytica
FEMS Immunol. Med. Microbiol.
45
137-142
2005
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651178
Labrou
The structure-function relatio ...
Hathewaya histolytica
Eur. J. Biochem.
271
983-992
2004
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651275
Gusman
Salivary histatin 5 is a poten ...
Hathewaya histolytica
FEBS Lett.
489
97-100
2001
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7
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652992
Gunther
Investigations on the enzyme s ...
Hathewaya histolytica
J. Org. Chem.
65
1672-1679
2000
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81590
Witte
Clostripain linker deletion va ...
Hathewaya histolytica
Curr. Microbiol.
33
281-286
1996
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81594
Witte
Heterologous expression of the ...
Hathewaya histolytica
Microbiology
140
1175-1182
1994
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81595
Ullmann
Kinetic characterization of af ...
Hathewaya histolytica
Biol. Chem. Hoppe-Seyler
375
89-92
1994
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824
Nishimura
Sensitivity of Escherichia col ...
Hathewaya histolytica
J. Biol. Chem.
268
13717-13722
1993
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81596
Beardshall
Effect of chymotrypsin on huma ...
Hathewaya histolytica
Regul. Pept.
40
1-12
1992
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81593
Kembhavi
Clostripain: characterization ...
Hathewaya histolytica
FEBS Lett.
283
277-280
1991
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9
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81589
Encontre
Chromatin core particle obtain ...
Hathewaya histolytica
J. Mol. Biol.
202
673-676
1988
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81579
Fortier
-
Substrate- and stereo-specific ...
Hathewaya histolytica
Biotechnol. Lett.
8
873-876
1986
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81580
Fortier
-
Peptide bond synthesis by clos ...
Hathewaya histolytica
Biotechnol. Lett.
8
777-782
1986
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6
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6
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2
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81581
Gilles
Primary structure of alpha-clo ...
Hathewaya histolytica
Eur. J. Biochem.
145
469-476
1984
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81582
Gilles
alpha-Clostripain. Chemical ch ...
Hathewaya histolytica
J. Biol. Chem.
254
1462-1468
1979
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81583
Giroux
Clostridiopeptidase B inhibiti ...
Hathewaya histolytica
Biochim. Biophys. Acta
525
429-437
1978
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81584
Mitchell
Cleavage at arginine residues ...
Hathewaya histolytica
Methods Enzymol.
47
165-170
1977
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81585
Emd
Five Sepharose-bound ligands f ...
Hathewaya histolytica
FEBS Lett.
77
51-56
1977
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81586
Kula
Consecutive use of omega-amino ...
Hathewaya histolytica
Biochem. Biophys. Res. Commun.
69
389-396
1976
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3
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81587
Siffert
Interaction of clostripain wit ...
Hathewaya histolytica
FEBS Lett.
66
114-119
1976
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81578
Mitchell
-
Clostripain ...
Hathewaya histolytica
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
3
699-719
1971
-
-
-
-
-
-
16
5
-
1
1
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81588
Cole
Specificity and mechanism of c ...
Hathewaya histolytica
Biochemistry
10
4246-4252
1971
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8
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81591
Mitchell
Purification and properties of ...
Hathewaya histolytica
J. Biol. Chem.
243
4683-4692
1968
-
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-
7
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1
1
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