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Literature summary for 3.4.22.59 extracted from

  • Yan, A.; Ren, C.; Chen, T.; Huo, D.; Jiang, X.; Sun, H.; Hu, C.
    A novel caspase-6 from sea cucumber Holothuria leucospilota Molecular characterization, expression analysis and apoptosis detection (2018), Fish Shellfish Immunol., 80, 232-240 .
    View publication on PubMed
Search for more literature for 3.4.22.59

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38570
-
 calculated from sequence Holothuria leucospilota

Organism

Organism UniProt Comment Textmining
Holothuria leucospilota A0A2I6STS0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood vessel transverse vessel Holothuria leucospilota
-
body wall
-
 Holothuria leucospilota
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coelomocyte expression of HLcaspase-6 mRNA in coelomocytes is significantly upregulated by lipopolysaccharides or polyriboinosinic-polyribocytidylic acid [poly (I:C)] challenge Holothuria leucospilota
-
cuvierian tubule
-
 Holothuria leucospilota
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intestine highest transcript level Holothuria leucospilota
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respiratory system
-
 Holothuria leucospilota
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rete mirabile
-
 Holothuria leucospilota
-

Synonyms

Synonyms Comment Organism
HLcaspase-6
-
 Holothuria leucospilota

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Holothuria leucospilota

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Holothuria leucospilota

Expression

Organism Comment Expression
Holothuria leucospilota in in vitro experiments, the expression of HLcaspase-6 mRNA in coelomocytes is significantly upregulated by lipopolysaccharides or polyriboinosinic-polyribocytidylic acid [poly (I:C)] challenge up

General Information

General Information Comment Organism
physiological function HLcaspase-6 might play important roles in the innate immune defense of sea cucumber against bacterial and viral infections. Overexpression of HLcaspase-6 d induces apoptosis and activates the p53 signal pathway Holothuria leucospilota