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Literature summary for 3.4.22.59 extracted from

  • Chen, G.G.; Chan, U.P.; Bai, L.C.; Fung, K.Y.; Tessier, A.; To, A.K.; Merchant, J.L.; Lai, P.B.
    ZBP-89 reduces the cell death threshold in hepatocellular carcinoma cells by increasing caspase-6 and S phase cell cycle arrest (2009), Cancer Lett., 283, 52-58.
    View publication on PubMedView publication on EuropePMC
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Activating Compound

Activating Compound Comment Organism Structure
additional information ZBP-89, a Kruppel-type, zinc finger transcription factor, induces caspase-6 activation leading to inhibition of cell death in hepatoccellular carcinoma cells, inhibition of caspase-6 abolishes the effect of ZBP-89 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens ZBP-89, a Kruppel-type, zinc finger transcription factor, induces caspase-6 activation leading to inhibition of cell death in hepatoccellular carcinoma cells, inhibition of caspase-6 abolishes the effect of ZBP-89 ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
HEP-3B cell
-
 Homo sapiens
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Hep-G2 cell
-
 Homo sapiens
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hepatoma cell
-
 Homo sapiens
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Huh-7 cell
-
 Homo sapiens
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PLC-PRF-5 cell
-
 Homo sapiens
-
SK-HEP-1 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information ZBP-89, a Kruppel-type, zinc finger transcription factor, induces caspase-6 activation leading to inhibition of cell death in hepatoccellular carcinoma cells, inhibition of caspase-6 abolishes the effect of ZBP-89 Homo sapiens ?
-
 ?