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Literature summary for 3.4.22.59 extracted from

  • Nyormoi, O.; Wang, Z.; Doan, D.; Ruiz, M.; McConkey, D.; Bar-Eli, M.
    Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cells (2001), Mol. Cell. Biol., 21, 4856-4867.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
transcription factor AP-2alpha + H2O Homo sapiens AP-2alpha is cleaved is at Asp19 of the sequence DRHD19 by caspase-6 before DNA framentation during TNF-alpha-induced apoptosis ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
transcription factor AP-2alpha + H2O cleaves at Asp19 of the sequence DRHD19 Homo sapiens ?
-
 ?
transcription factor AP-2alpha + H2O AP-2alpha is cleaved is at Asp19 of the sequence DRHD19 by caspase-6 before DNA framentation during TNF-alpha-induced apoptosis Homo sapiens ?
-
 ?