Literature summary for 3.4.22.38 extracted from

Munoz-Torres, M.; Reyes-Garcia, R.; Mezquita-Raya, P.; Fernandez-Garcia, D.; Alonso, G.; Luna, J.d.e..D.; Ruiz-Requena, M.E.; Escobar-Jimenez, F.
Serum cathepsin K as a marker of bone metabolism in postmenopausal women treated with alendronate (2009), Maturitas, 64, 188-192.

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Application

Application	Comment	Organism
medicine	serum cathepsin K is a marker of bone metabolism in postmenopausal women treated with alendronate	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
serum	-	Homo sapiens	-

Expression

Organism	Comment	Expression
Homo sapiens	serum cathepsin K decreases gradually after alendronate treatment (17% at 3 months, 22% at 6 months and 41% at 12 months)	down
Homo sapiens	serum cathepsin K levels are higher in postmenopausal women with osteoporosis compared with healthy postmenopausal women and premenopausal women	up

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Release 2023.1 (January 2023)