Literature summary for 3.4.22.29 extracted from

Deszcz, L.; Seipelt, J.; Vassilieva, E.; Roetzer, A.; Kuechler, E.
Antiviral activity of caspase inhibitors: effect on picornaviral 2A proteinase (2004), FEBS Lett., 560, 51-55.

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Inhibitors

Inhibitors	Comment	Organism	Structure
benzyloxycarbonyl-Ile-Glu-Thr-Asp(OMe)-fluoromethylketone	50% inhibition at 0.0077 mM, delay of self-cleavage	picornaviridae
benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone	50% inhibition at 0.0056 mM, delay of self-cleavage	picornaviridae
additional information	no inhibition by unmethylated benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone or benzyloxycarbonyl-Ile-Glu-Thr-Asp-fluoromethylketone	picornaviridae

Organism

Organism	UniProt	Comment	Textmining
picornaviridae	-	-	-

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Release 2023.1 (January 2023)