Literature summary for 3.4.21.B7 extracted from

Jani, P.K.; Schwaner, E.; Kajdacsi, E.; Debreczeni, M.L.; Ungai-Salanki, R.; Dobo, J.; Doleschall, Z.; Rigo, J.; Geiszt, M.; Szabo, B.; Gal, P.; Cervenak, L.
Complement MASP-1 enhances adhesion between endothelial cells and neutrophils by up-regulating E-selectin expression (2016), Mol. Immunol., 75, 38-47 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in HUVEC cell	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P48740	-	-

Synonyms

Synonyms	Comment	Organism
MASP-1	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	recombinant expression of MASP-1 in HUVECs decreases the expression of ICAM-2 and increases that of E-selectin, whereas ICAM-1, VCAM-1 and P-selectin expression remain unchanged. These changes result in increased adherence between differentiated PLB-985 cells and endothelial cells. Complement MASP-1 can increase adhesion between neutrophils and endothelial cells ina direct fashion	Homo sapiens

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Release 2023.1 (January 2023)