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Literature summary for 3.4.21.B7 extracted from

  • Thiel, S.; Jensen, L.; Degn, S.E.; Nielsen, H.J.; Gal, P.; Dobo, J.; Jensenius, J.C.
    Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components (2012), Clin. Exp. Immunol., 169, 38-48.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
75000
-
x * 75000, SDS-PAGE Homo sapiens
600000
-
large enzyme complexes in plasma, gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P48740
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma immunohistochemic determination of enzyme levels in plasma samples and variations over time, MASP-1 levels after the induction of an acute-phase response by operation for colorectal cancer show an initial short decrease, concomitant with an increase in C-reactive protein levels, followed by an increase, doubling the MASP-1 concentration after 2 days, overview Homo sapiens
-

Subunits

Subunits Comment Organism
? x * 75000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
MASP-1
-
Homo sapiens
MBL-associated serine protease-1
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme is associated with humoral pattern-recognition molecules, overview Homo sapiens