Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.B7 extracted from

  • Kocsis, A.; Kekesi, K.A.; Szasz, R.; Vegh, B.M.; Balczer, J.; Dobo, J.; Zavodszky, P.; Gal, P.; Pal, G.
    Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation (2010), J. Immunol., 185, 4169-4178.
    View publication on PubMed
Search for more literature for 3.4.21.B7

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
cyclic GICSRSLPPICIPD
-
 Homo sapiens
GICSRSLPPICIPD
-
 Homo sapiens
additional information MASP-1 is not inhibited by sunflower MASP inhibitor-2 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
complement component C2 + H2O Homo sapiens
-
 ?
-
 ?
complement component C3 + H2O Homo sapiens
-
 ?
-
 ?
factor XIII + H2O Homo sapiens
-
 ?
-
 ?
Fibrinogen + H2O Homo sapiens
-
 ?
-
 ?
protease-activated receptor 4 + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C2 + H2O
-
 Homo sapiens ?
-
 ?
complement component C3 + H2O
-
 Homo sapiens ?
-
 ?
factor XIII + H2O
-
 Homo sapiens ?
-
 ?
Fibrinogen + H2O
-
 Homo sapiens ?
-
 ?
L-lysine thiobenzyl ester + H2O C3647 Homo sapiens ?
-
 ?
protease-activated receptor 4 + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
MASP-1
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000065
-
 GICSRSLPPICIPD in 20 mM HEPES, 145 mM NaCl, 5 mM CaCl2, and 0.05% (v/v) Triton X-100, at pH 7.6 and 22°C Homo sapiens
0.000275
-
 cyclic GICSRSLPPICIPD in 20 mM HEPES, 145 mM NaCl, 5 mM CaCl2, and 0.05% (v/v) Triton X-100, at pH 7.6 and 22°C Homo sapiens