Literature summary for 3.4.21.B60 extracted from

Schneider, M.A.; Richtmann, S.; Gruending, A.R.; Wrenger, S.; Welte, T.; Meister, M.; Kriegsmann, M.; Winter, H.; Muley, T.; Janciauskiene, S.
Transmembrane serine protease 2 is a prognostic factor for lung adenocarcinoma (2022), Int. J. Oncol., 60, 39 .

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Application

Application	Comment	Organism
medicine	in tumor and adjacent lung tissues from non-small cell lung cancer patients, lower TMPRSS2 expression in tumor compared to adjacent non-tumor tissues is linked to a poor overall survival in patients with adenocarcinoma and those who are current smokers. A slight negative correlation between full-length TMPRSS2 and alpha-1-antitrypsin in non-tumor tissues seems to be related to smoking status	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O15393	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lung	-	Homo sapiens	-

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Release 2023.1 (January 2023)