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Literature summary for 3.4.21.B6 extracted from

  • Chen, L.M.; Hatfield, M.L.; Fu, Y.Y.; Chai, K.X.
    Prostasin regulates iNOS and cyclin D1 expression by modulating protease-activated receptor-2 signaling in prostate epithelial cells (2009), Prostate, 69, 1790-1801.
    View publication on PubMed
Search for more literature for 3.4.21.B6

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
 SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
BPH-1 cell a benign prostatic hyperplasia cell line Homo sapiens
-
LNCaP cell
-
 Homo sapiens
-
additional information prostatin is not expressed in PC-3 cells Homo sapiens
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prostate gland epithelium
-
 Homo sapiens
-

General Information

General Information Comment Organism
malfunction prostasin silencing in BPH-1 cells is associated with up-regulation of iNOS, ICAM-1, interleukin-6, and interleukin-8, and down-regulation of cyclin D1, as well as reduced proliferation and invasion Homo sapiens
physiological function prostasin regulates iNOS and cyclin D1 expression by modulating protease-activated receptor-2 signaling in prostate epithelial cells. Prostasin plays a negative regulatory role on protease-activated receptor-2-mediated signaling in prostate epithelial cell Homo sapiens