Literature summary for 3.4.21.B4 extracted from

Plasman, K.; Demol, H.; Bird, P.I.; Gevaert, K.; Van Damme, P.
Substrate specificities of the granzyme tryptases A and K (2014), J. Proteome Res., 13, 6067-6077.

Search for more literature for 3.4.21.B4

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P49863	-	-
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	substrate identification analysing substrate repertoire and specificity by N-terminal COFRADIC assisted N-terminomics on the homologous enzyme. Comparisons of specificity profiles of human and mouse enzymes revealing only subtle differences and pointed to substrate occupancies in the P1, P1', and P2' position as the main determinants for substrate recognition, overview	Mus musculus	?	-	?
additional information	substrate identification analysing substrate repertoire and specificity by N-terminal COFRADIC assisted N-terminomics on the homologous enzyme. Comparisons of specificity profiles of human and mouse enzymes revealing only subtle differences and pointed to substrate occupancies in the P1, P1', and P2' position as the main determinants for substrate recognition, overview	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
granzyme tryptase K	-	Mus musculus
granzyme tryptase K	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	the enzyme has a role in cytotoxic and inflammatory processes	Mus musculus
physiological function	the enzyme has a role in cytotoxic and inflammatory processes	Homo sapiens

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Release 2023.1 (January 2023)