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Literature summary for 3.4.21.B28 extracted from

  • Gunderson, A.; Yamazaki, T.; McCarty, K.; Phillips, M.; Alice, A.; Bambina, S.; Zebertavage, L.; Friedman, D.; Cottam, B.; Newell, P.; Gough, M.; Crittenden, M.; Van der Veken, P.; Young, K.
    Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma (2019), PLoS ONE, 14, e0211117 .
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine targeting fibroblast activation protein and cancer-associated fibroblasts in combination with radiation is capable of enhancing anti-tumor T cell infiltrate and function, but does not result in sufficient tumor clearance to extend survival Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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