Cloned (Comment) | Organism |
---|---|
wild-type, mutant with deletion of a dipeptide and mutant with deletion of a hexapeptide, expressed in COS cells | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
35000 | - |
SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | involved in granule exocytosis form of target cell death induced by cytotoxic lymphocytes | ? | - |
? | |
Protein + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
proteolytic modification | first step requires cleavage of signal peptide resulting in an inactive zymogen with an amino-terminal activation propeptide, which must then be cleaved by another protease to generate a biologically active enzyme | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymphocyte | CD3- large granular lymphocyte with natural killer cell activity | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | hydrolyzes substrates containing a methionine-side chain at P1 | Homo sapiens | ? | - |
? | |
additional information | involved in granule exocytosis form of target cell death induced by cytotoxic lymphocytes | Homo sapiens | ? | - |
? | |
N-tert-butoxycarbonyl-Ala-Ala-Met thiobenzyl ester + H2O | activity only occurs with deletion mutants, but not with wild-type enzyme | Homo sapiens | N-tert-butoxycarbonyl-Ala-Ala-Met + phenylmethanethiol | - |
? | |
Protein + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
hMet-1 | - |
Homo sapiens |
Met-ase-1 | - |
Homo sapiens |