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Literature summary for 3.4.21.B10 extracted from
- Study of kallikrein-related peptidase 6 (KLK6) and its complex with alpha1-antitrypsin in biological fluids (2017), Clin. Chem. Lab. Med., 55, 1385-1396 .
Application
| Application | Comment | Organism |
|---|---|---|
| diagnostics | KLK6 is present in biological fluids either as free form, or bound to alpha1-antitrypsin, and the bound form performs better than total KLK6 as a biomarker of ovarian carcinoma | Homo sapiens |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q92876 | - |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | differential glycosylation of KLK6 is identified in ascites fluid obtained from ovarian cancer patients, suggesting the presence of unique KLK6 isoforms in biological samples | Homo sapiens |
| proteolytic modification | the enzyme is synthesized as a preproenzyme, mainly in tissues of the central nervous system, and secreted as an inactive precursor | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood serum | - |
Homo sapiens | - |
| ovary cancer cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| kallikrein-related peptidase 6 | - |
Homo sapiens |
| KLK6 | - |
Homo sapiens |
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