Literature summary for 3.4.21.B10 extracted from

Prezas, P.; Arlt, M.J.; Viktorov, P.; Soosaipillai, A.; Holzscheiter, L.; Schmitt, M.; Talieri, M.; Diamandis, E.P.; Krueger, A.; Magdolen, V.
Overexpression of the human tissue kallikrein genes KLK4, 5, 6, and 7 increases the malignant phenotype of ovarian cancer cells (2006), Biol. Chem., 387, 807-811.

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Application

Application	Comment	Organism
medicine	tumor-associated overexpression of tissue kallikreins contributes to ovarian cancer progression. Possibily effects observed may be due to the activity of only some of the four kallikreins hK4, hK5, hK6, and hK7 under survey	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
OV-MZ-6 ovarian cancer cells stably co-transfected with pRc/RSV-plasmid expressing hK4, hK5, hK6, and hK7. Overexpression in OV-MZ-6 ovarian cancer cells and in the peritoneum of nude mice, inoculated with OV-KLK4+5+6+7 cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
ovary cancer cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
hK6	expression from KLK6 gene	Homo sapiens
KLK6	-	Homo sapiens

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Release 2023.1 (January 2023)