Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WPC3 | protease subunit ClpP2 | - |
Mycobacterium tuberculosis | P9WPC5 | protease subunit ClpP1 | - |
Mycobacterium tuberculosis H37Rv | P9WPC3 | protease subunit ClpP2 | - |
Mycobacterium tuberculosis H37Rv | P9WPC5 | protease subunit ClpP1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
LacZ + H2O | - |
Mycobacterium tuberculosis | ? | proteolytic subunit ClpP2 over-expression induces degradation of untagged LacZ | ? | |
LacZ + H2O | - |
Mycobacterium tuberculosis H37Rv | ? | proteolytic subunit ClpP2 over-expression induces degradation of untagged LacZ | ? | |
additional information | the SsrA tag directs proteins to degradation by both ClpP1 and ClpP2. The terminal three residues of the ssrA-tag sequence are LAA. A LAA-tag is sufficient to direct proteins into the degradation pathway | Mycobacterium tuberculosis | ? | - |
? | |
additional information | the SsrA tag directs proteins to degradation by both ClpP1 and ClpP2. The terminal three residues of the ssrA-tag sequence are LAA. A LAA-tag is sufficient to direct proteins into the degradation pathway | Mycobacterium tuberculosis H37Rv | ? | - |
? | |
SsrA-tagged LacZ + H2O | both proteolytic subunits ClpP1 and ClpP2 degrade SsrA-tagged LacZ | Mycobacterium tuberculosis | ? | - |
? | |
SsrA-tagged LacZ + H2O | both proteolytic subunits ClpP1 and ClpP2 degrade SsrA-tagged LacZ | Mycobacterium tuberculosis H37Rv | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ATP-dependent Clp protease proteolytic subunit 1 | - |
Mycobacterium tuberculosis |
ATP-dependent Clp protease proteolytic subunit 2 | - |
Mycobacterium tuberculosis |
ClpP1 | - |
Mycobacterium tuberculosis |
ClpP2 | - |
Mycobacterium tuberculosis |
Organism | Comment | Expression |
---|---|---|
Mycobacterium tuberculosis | proteolytic subunits ClpP1 and ClpP2 are co-expressed under normal growth conditions with a single promoter region for the clpP1P2 operon | additional information |