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Literature summary for 3.4.21.88 extracted from

  • Jian, H.; Xiong, L.; He, Y.; Xiao, X.
    The regulatory function of LexA is temperature-dependent in the deep-sea bacterium Shewanella piezotolerans WP3 (2015), Front. Microbiol., 6, 627 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.88

Cloned(Commentary)

Cloned (Comment) Organism
gene lexA, quantitative enzyme PCR expression analysis Shewanella piezotolerans

Protein Variants

Protein Variants Comment Organism
additional information construction of a lexA deletion strain WP3DELTAlexA, no growth defect is observed. 481 and 108 genes are differentially expressed at 20°C and 4°C, respectively, as demonstrated by comparative whole genome microarray analysis Shewanella piezotolerans

Organism

Organism UniProt Comment Textmining
Shewanella piezotolerans B8CUX0
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Shewanella piezotolerans JCM 13877 B8CUX0
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Shewanella piezotolerans WP3 B8CUX0
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information LexA is a DNA-binding protein Shewanella piezotolerans ?
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 ?
additional information LexA is a DNA-binding protein Shewanella piezotolerans WP3 ?
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 ?
additional information LexA is a DNA-binding protein Shewanella piezotolerans JCM 13877 ?
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 ?

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
additional information
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 the SOS regulator is significantly influenced by environmental temperatures Shewanella piezotolerans

Expression

Organism Comment Expression
Shewanella piezotolerans transcription of gene lexA is upregulated during cold acclimatization and after cold shock up

General Information

General Information Comment Organism
malfunction a lexA deletion strain WP3DELTAlexA shows no growth defects at 4-20°C Shewanella piezotolerans
physiological function LexA is a DNA-binding protein and a SOS regulator. SOS is a formidable strategy used by bacteria against various environmental stresses. The LexA protein is a transcriptional regulator situated in the central position of the SOS pathway Shewanella piezotolerans