Literature summary for 3.4.21.67 extracted from

Lee, Y.S.; Park, S.C.; Goldberg, A.L.; Chung, C.H.
Protease So from Escherichia coli preferentially degrades oxidatively damaged glutamine synthetase (1988), J. Biol. Chem., 263, 6643-6646.

Search for more literature for 3.4.21.67

Inhibitors

Inhibitors	Comment	Organism	Structure
EDTA	-	Escherichia coli

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ca2+	stimulates degradation of oxidatively damaged glutamine synthetase, even so casein hydrolysis is not affected	Escherichia coli
Mg2+	stimulates degradation of oxidatively damaged glutamine synthetase, even so casein hydrolysis is not affected	Escherichia coli
Mn2+	stimulates degradation of oxidatively damaged glutamine synthetase, even so casein hydrolysis is not affected	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Oxidatively damaged glutamine synthetase + H2O	to acid-soluble peptides, degradation is 5-10times faster than with the native glutamine synthetase	Escherichia coli	?	-	?

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Release 2023.1 (January 2023)