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Literature summary for 3.4.21.6 extracted from

  • Dhar, A.; Sadiq, F.; Anstee, Q.M.; Levene, A.P.; Goldin, R.D.; Thursz, M.R.
    Thrombin and factor Xa link the coagulation system with liver fibrosis (2018), BMC Gastroenterol., 18, 60 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.6

Inhibitors

Inhibitors Comment Organism Structure
rivaroxaban
-
 Homo sapiens
rivaroxaban
-
 Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatic stellate cell
-
 Mus musculus
-
hepatic stellate cell
-
 Homo sapiens
-
LX-2 cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
factor Xa
-
 Mus musculus
factor Xa
-
 Homo sapiens
FXa
-
 Mus musculus
FXa
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction enzyme inhibition reduces thioacetamide-induced murine liver fibrosis Mus musculus
physiological function the enzyme promotes stellate cell contractility and activation Homo sapiens