Inhibitors | Comment | Organism | Structure |
---|---|---|---|
chymostatin | - |
Homo sapiens | |
chymostatin | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | Homo sapiens | - |
angiotensin II + His-Leu | - |
? | |
angiotensin I + H2O | Mus musculus | - |
angiotensin II + His-Leu | - |
? | |
biglycan + H2O | Homo sapiens | - |
? | - |
? | |
biglycan + H2O | Mus musculus | - |
? | - |
? | |
heat shock protein 70 + H2O | Homo sapiens | - |
? | - |
? | |
heat shock protein 70 + H2O | Mus musculus | - |
? | - |
? | |
HMGB1 + H2O | Homo sapiens | - |
? | - |
? | |
HMGB1 + H2O | Mus musculus | - |
? | - |
? | |
interleukin-33 + H2O | Homo sapiens | - |
? | - |
? | |
interleukin-33 + H2O | Mus musculus | - |
? | - |
? | |
additional information | Homo sapiens | interleukin-7, interleukin-22, GM-CSF, and CCL2 are resistant to chymase degradation | ? | - |
? | |
additional information | Mus musculus | interleukin-7, interleukin-22, GM-CSF, and CCL2 are resistant to chymase degradation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P23946 | - |
- |
Mus musculus | P21812 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA agarose bead chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mast cell | - |
Homo sapiens | - |
mast cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | - |
Homo sapiens | angiotensin II + His-Leu | - |
? | |
angiotensin I + H2O | - |
Mus musculus | angiotensin II + His-Leu | - |
? | |
biglycan + H2O | - |
Homo sapiens | ? | - |
? | |
biglycan + H2O | - |
Mus musculus | ? | - |
? | |
heat shock protein 70 + H2O | - |
Homo sapiens | ? | - |
? | |
heat shock protein 70 + H2O | - |
Mus musculus | ? | - |
? | |
HMGB1 + H2O | - |
Homo sapiens | ? | - |
? | |
HMGB1 + H2O | - |
Mus musculus | ? | - |
? | |
interleukin-33 + H2O | - |
Homo sapiens | ? | - |
? | |
interleukin-33 + H2O | - |
Mus musculus | ? | - |
? | |
additional information | interleukin-7, interleukin-22, GM-CSF, and CCL2 are resistant to chymase degradation | Homo sapiens | ? | - |
? | |
additional information | interleukin-7, interleukin-22, GM-CSF, and CCL2 are resistant to chymase degradation | Mus musculus | ? | - |
? | |
N-succinyl-L-Leu-L-Leu-L-Val-L-Tyr-4-nitroanilide + H2O | - |
Homo sapiens | N-succinyl-L-Leu-L-Leu-L-Val-L-Tyr + 4-nitroaniline | - |
? | |
N-succinyl-L-Leu-L-Leu-L-Val-L-Tyr-4-nitroanilide + H2O | - |
Mus musculus | N-succinyl-L-Leu-L-Leu-L-Val-L-Tyr + 4-nitroaniline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mast cell chymase | - |
Homo sapiens |
mast cell chymase | - |
Mus musculus |
MCPT-4 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | mast cell chymase degrades alarmins and may limit inflammation | Homo sapiens |
physiological function | mast cell chymase degrades alarmins and may limit inflammation | Mus musculus |