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Literature summary for 3.4.21.34 extracted from

  • Abid, K.; Rochat, B.; Lassahn, P.G.; Stoecklin, R.; Michalet, S.; Brakch, N.; Aubert, J.F.; Vatansever, B.; Tella, P.; De Meester, I.; Grouzmann, E.
    Kinetic study of neuropeptide Y (NPY) proteolysis in blood and identification of NPY3-35: a new peptide generated by plasma kallikrein (2009), J. Biol. Chem., 284, 24715-24724.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.34

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0281
-
 neuropeptide Y3-36 at 37°C Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-
serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
neuropeptide Y3-36 + H2O optimal kallikrein concentration is 5 microg/ml, cleavage of around 70% of neuropeptide Y3-36. Higher concentrations of kallikrein conversely results in a decrease of NPY3-35 levels without an increase of neuropeptide Y3-36 levels, suggesting that high concentrations of kallikrein enable additional and nonspecific neuropeptide Y cleavages Homo sapiens neuropeptide Y3-35 + L-tyrosine
-
 ?

Synonyms

Synonyms Comment Organism
kallikrein
-
 Homo sapiens
plasma kallikrein
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function plasma kallikrein is the carboxypeptidase/esterase enzyme responsible for tyrosinamide removal from neuropeptide Y Homo sapiens