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Literature summary for 3.4.21.21 extracted from

  • Gajsiewicz, J.M.; Nuzzio, K.M.; Rienstra, C.M.; Morrissey, J.H.
    Tissue factor residues that modulate magnesium-dependent rate enhancements of the tissue factor/factor VIIa complex (2015), Biochemistry, 54, 4665-4671 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.21

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
additional information Mg2+ alone does not significantly influence the rate of factor X activation by the enzyme. The presence of tissue factor is required for Mg2+ to enhance the rate of factor X activation by the enzyme Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
factor IX + H2O Homo sapiens
-
 factor IXa + ?
-
 ?
Factor X + H2O Homo sapiens
-
 Factor Xa + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Chromozym tissue plasminogen activator + H2O i.e. N-methylsulfonyl-D-Phe-Gly-Arg-4-nitranilide acetate Homo sapiens ?
-
 ?
factor IX + H2O
-
 Homo sapiens factor IXa + ?
-
 ?
Factor X + H2O
-
 Homo sapiens Factor Xa + ?
-
 ?

Synonyms

Synonyms Comment Organism
factor VIIa
-
 Homo sapiens
FVIIa
-
 Homo sapiens