Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CD40L + H2O | Homo sapiens | low activity | ? | - |
? | |
human recombinant B-cell activating factor + H2O | Homo sapiens | low activity | ? | - |
? | |
interleukin-15 + H2O | Homo sapiens | - |
? | - |
? | |
interleukin-17A + H2O | Homo sapiens | low activity | ? | - |
? | |
interleukin-18 + H2O | Homo sapiens | - |
? | - |
? | |
interleukin-2 + H2O | Homo sapiens | low activity | ? | - |
? | |
interleukin-21 + H2O | Homo sapiens | low activity | ? | - |
? | |
interleukin-22 + H2O | Homo sapiens | low activity | ? | - |
? | |
interleukin-24 + H2O | Homo sapiens | low activity | ? | - |
? | |
interleukin-3 + H2O | Homo sapiens | - |
? | - |
? | |
interleukin-31 + H2O | Homo sapiens | efficient substrate | ? | - |
? | |
interleukin-33 + H2O | Homo sapiens | - |
? | - |
? | |
interleukin-6 + H2O | Homo sapiens | efficient substrate | ? | - |
? | |
interleukin-7 + H2O | Homo sapiens | efficient substrate | ? | - |
? | |
membrane-bound stem cell factor + H2O | Homo sapiens | - |
? | - |
? | |
additional information | Homo sapiens | the extended cleavage sites for the enzyme contain about 8 amino acids, and cleavage normally occurs after an aromatic amino acid (phenylalanine, tyrosine and tryptophan or leucine) in the P1 substrate position | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CD40L + H2O | low activity | Homo sapiens | ? | - |
? | |
human recombinant B-cell activating factor + H2O | low activity | Homo sapiens | ? | - |
? | |
interleukin-15 + H2O | - |
Homo sapiens | ? | - |
? | |
interleukin-17A + H2O | low activity | Homo sapiens | ? | - |
? | |
interleukin-18 + H2O | - |
Homo sapiens | ? | - |
? | |
interleukin-2 + H2O | low activity | Homo sapiens | ? | - |
? | |
interleukin-21 + H2O | low activity | Homo sapiens | ? | - |
? | |
interleukin-22 + H2O | low activity | Homo sapiens | ? | - |
? | |
interleukin-24 + H2O | low activity | Homo sapiens | ? | - |
? | |
interleukin-3 + H2O | - |
Homo sapiens | ? | - |
? | |
interleukin-31 + H2O | efficient substrate | Homo sapiens | ? | - |
? | |
interleukin-33 + H2O | - |
Homo sapiens | ? | - |
? | |
interleukin-6 + H2O | efficient substrate | Homo sapiens | ? | - |
? | |
interleukin-7 + H2O | efficient substrate | Homo sapiens | ? | - |
? | |
membrane-bound stem cell factor + H2O | - |
Homo sapiens | ? | - |
? | |
additional information | the extended cleavage sites for the enzyme contain about 8 amino acids, and cleavage normally occurs after an aromatic amino acid (phenylalanine, tyrosine and tryptophan or leucine) in the P1 substrate position | Homo sapiens | ? | - |
? | |
additional information | no activity with interleukin-4, interleukin-5, or interleukin-10 | Homo sapiens | ? | - |
? |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme functions in regulating excessive inflammation | Homo sapiens |