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Literature summary for 3.4.21.20 extracted from
- Cathepsin G cleaves and activates IL-36gamma and promotes the inflammation of psoriasis (2019), Drug Des. Devel. Ther., 13, 581-588 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | enzyme inhibitors are used as drugs for psoriasis | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| interleukin-36gamma + H2O | Homo sapiens | - |
? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HaCaT cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| interleukin-36gamma + H2O | - |
Homo sapiens | ? | - |
? | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme cleaves and activates recombinant human full length interleukin-36gamma to promote CXCL-1 and CXCL-8 expression by human keratinocytes | Homo sapiens |
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