Literature summary for 3.4.21.122 extracted from

Kawasumi, T.; Takeno, S.; Ishino, T.; Ueda, T.; Hamamoto, T.; Takemoto, K.; Horibe, Y.; Takashi, O.
Co-expression and localization of angiotensin-converting enzyme-2 (ACE2) and the transmembrane serine protease 2 (TMPRSS2) in paranasal ciliated epithelium of patients with chronic rhinosinusitis (2022), Am. J. Rhinol. Allergy, 36, 313-322 .

Search for more literature for 3.4.21.122

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O15393	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
paranasal ciliated epithelium	angiotensin-converting enzyme-2 (ACE2) and the transmembrane serine protease 2 (TMPRSS2) are co-expressed in the ciliated epithelium of patients with eosinophilic chronic rhinosinusitis	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
TMPRSS2	-	Homo sapiens
transmembrane serine protease 2	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	ECRS patients with type 2 inflammation show decreased ACE2 and TMPRSS2 expressions in their sinus mucosa	down

General Information

General Information	Comment	Organism
metabolism	angiotensin-converting enzyme-2 (ACE2) and the transmembrane serine protease 2 (TMPRSS2) seem to be positively related to IFN-gamma and TNF-alpha production in chronic rhinosinusitis patient. ACE2 and TMPRSS2 are co-expressed in the ciliated epithelium of their paranasal mucosa, implicating the paranasal epithelium as a portal for initial infection and transmission	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)