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Literature summary for 3.4.21.122 extracted from

  • Shirato, K.; Kawase, M.; Matsuyama, S
    Wild-type human coronaviruses prefer cell-surface TMPRSS2 to endosomal cathepsins for cell entry (2018), Virology, 517, 9-15 .
    View publication on PubMed

Application

Application Comment Organism
medicine clinical isolates of coronaviruses HCoV-OC43 and -HKU1 prefer the cell-surface protease TMRRSS2 over endosomal cathepsins for host cell entry. Virus adaptation in cultured cells after isolation alters the route of cell entry and such modified isolates might not reflect the HCoVs of the natural world Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Homo sapiens O15393
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Source Tissue

Source Tissue Comment Organism Textmining