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Literature summary for 3.4.21.122 extracted from
- Phenotypic analysis of mice lacking the Tmprss2-encoded protease (2006), Mol. Cell. Biol., 26, 965-975 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q9JIQ8 | - |
- |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | compared to wild-type littermates, Tmprss2-/- mice develop normally, survive to adulthood with no differences in protein levels of prostatic secretions, and exhibit no discernible abnormalities in organ histology or function. Loss of TMPRSS2 activity does not influence fertility, reduce survival, result in prostate hyperplasia or carcinoma, or alter prostatic luminal epithelial cell regrowth following castration and androgen replacement | Mus musculus |
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Release 2023.1 (January 2023)
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