Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q9JIQ8 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
alveolar cell type I | Tmprss2 and Tmprss4 are coexpressed in alveolar and bronchial regions | Mus musculus | - |
alveolar cell type II | Tmprss2 and Tmprss4 are coexpressed in alveolar and bronchial regions | Mus musculus | - |
bronchus | Tmprss2 and Tmprss4 are coexpressed in alveolar and bronchial regions | Mus musculus | - |
General Information | Comment | Organism |
---|---|---|
physiological function | after infection of Tmprss2 knockout mice with an H3N2 influenza virus, only a slight increase in survival is observed. Tmprss2-/- Tmprss4-/-x02double-knockout mice show a remarkably reduced virus spread and lung pathology, in addition to reduced body weight loss and mortality | Mus musculus |