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Literature summary for 3.4.21.122 extracted from
- The human transmembrane protease serine 2 is necessary for the production of group 2 influenza A virus pseudotypes (2012), J. Mol. Genet. Med., 7, 309-314 .
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | use of TMPRSS2 to produce high titre influenza hemagglutixadnin lentiviral pseudotypes from Group 2 influenza viruses. These lentiviral pseudotypes transduce HEK293T/17 cells with high efficiency. The Group 2 influenza pseudotype particles can be used as surrogate antigens in neutralization assays and are efficiently neutralized by corresponding influenza virus reference sera | Homo sapiens |
| medicine | TMPRSS2 is necessary for the functional activation, in vitro, of both the hemagglutinin of human seasonal influenza and other Group 2 HA influenza strains | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O15393 | - |
- |
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Release 2023.1 (January 2023)
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