Application | Comment | Organism |
---|---|---|
medicine | TMPRSS2-ERG is the most common gene fusion in prostate cancer. 74% (117/158) of the prostate adenocarcinomas analyzed were positive for the TMPRSS2-ERG and/or telomerase TERT expression. Significantly higher expression of ERG is detected in TMPRSS2-ERG-positive tumors, whereas more intense expression of SPINK1 is characteristic for the TMPRSS2-ERG negative tumors. The cases negative for both transcripts, TMPRSS2-ERG and TERT, rarely recurr and show significantly longer biochemical recurrence-free period as compared to the TMPRSS2-ERG and/or TERT-positive cases | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O15393 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
prostate cancer cell line | - |
Homo sapiens | - |
prostate gland | - |
Homo sapiens | - |