Inhibitors | Comment | Organism | Structure |
---|---|---|---|
PF-429242 | potent S1P inhibitor both in vitro and in cell-based assays, PF-429242 inhibits S1P-mediated processing of arenavirus arenavirus glycoprotein precursor protein | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
Golgi apparatus | - |
Homo sapiens | 5794 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Lassa virus glycoprotein precursor protein + H2O | Homo sapiens | - |
peripheral virion attachment protein GP1 + fusion-active transmembrane protein GP2 | Arg-Arg-Leu-Leu + Gly-Thr-Phe | ? | |
lymphocytic choriomeningitis virus glycoprotein precursor protein + H2O | Homo sapiens | - |
peripheral virion attachment protein GP1 + fusion-active transmembrane protein GP2 | Arg-Arg-Leu-Ala + Gly-Thr-Phe | ? | |
succinyl-YISRRLL-7-amido-4-methylcoumarin + H2O | Homo sapiens | - |
succinyl-YISRRLL + 7-amino-4-methylcoumarin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Lassa virus glycoprotein precursor protein + H2O | - |
Homo sapiens | peripheral virion attachment protein GP1 + fusion-active transmembrane protein GP2 | Arg-Arg-Leu-Leu + Gly-Thr-Phe | ? | |
lymphocytic choriomeningitis virus glycoprotein precursor protein + H2O | - |
Homo sapiens | peripheral virion attachment protein GP1 + fusion-active transmembrane protein GP2 | Arg-Arg-Leu-Ala + Gly-Thr-Phe | ? | |
succinyl-YISRRLL-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | succinyl-YISRRLL + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
S1P | - |
Homo sapiens |