Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-[6-(6-methyl-3H-indol-2-yl)pyridin-2-yl]cyclohexan-1-ol | compounds exhibits inhibition of invasion and migration of hepsin-overexpressing cell line. The selective inhibition of hepsin is likely due to interactions of the midine group at the S1 site with the cyclohexyl ring from the 2-aryl group projecting towards the S1' site and the tert-hydroxyl group interacting with His57 side-chain | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P05981 | - |
- |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0001 | - |
1-[6-(6-methyl-3H-indol-2-yl)pyridin-2-yl]cyclohexan-1-ol | pH not specified in the publication, temperature not specified in the publication | Homo sapiens |