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Literature summary for 3.4.21.106 extracted from
- Hepsin activates prostasin and cleaves the extracellular domain of the epidermal growth factor receptor (2010), Mol. Cell. Biochem., 337, 259-266.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| FT-293 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| epidermal growth factor receptor + H2O | hepsin cleavage of epidermal growth factor receptor is not dependent on receptor tyrosine phosphorylation | Homo sapiens | ? | - |
? |  |
| prostasin pro-peptide + H2O | hepsin activates prostasin, cleavage occurs at Arg44 | Homo sapiens | prostasin | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TMPRSS1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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